I gave a short presentation at the NYU CTSI Translational Research in Progress seminar this week about our sequencing work on strains of Streptococcus mutans associated with severe tooth decay in children. We sequenced and did de novo assembly on each of 20 strains, then did an in silico subtraction to find unique genomic elements associated with health or disease.
the details are in this PDF file:
netSmooth – network-smoothing based imputation for single cell RNA-seq - Single cell RNA-seq (scRNA-seq) experiments suffer from a range of characteristic technical biases, such as dropouts (zero or near zero counts) and high...
5 hours ago